个人简介

李明博士,现任博彩公司排名-博彩公司评级 教授,博士生导师。国家海外高层次引进人才,中山大学百人计划中青年杰出引进人才,获聘中山大学“逸仙学者计划”优秀学者岗位。2014年获得美国奥本大学昆虫学博士学位;2023年7月加入博彩公司排名-博彩公司评级 。已发表SCI论文46篇,包括Proceedings of the National Academy of Sciences,eLife,Nature communications等知名杂志,已建构700+转基因昆虫品系。

有害生物是指会对人类造成竞争威胁的生物。包括医学上重要的蚊、蜱、蝇、蝽等,以及农林上重要的蚜、螨、蝶、蛾等,这些有害生物危害人类的健康和生命安全,造成巨大的经济损失。

课题组整合昆虫学、基因组学、遗传学、分子生物学和基因工程,1) 建构基于转基因以及基因编辑技术的新型有害生物(医学和农业)研究平台;2) 探索/挖掘有害生物基因的功能以及与病毒、共生菌等的互作机制;3) 开发新型有害生物种群替代和种群防控技术,以降低有害生物给人类健康带来的危害和减少经济损失。

学术成果

代表性学术论著

1.Ming Li, Xuechun Feng, William R Reid, Fang Tang, Nannan Liu. Multiple-P450 Gene Co-Up-Regulation in the Development of Permethrin Resistance in the House Fly, Musca domestica. 2023. International Journal of Molecular Sciences

//www.mdpi.com/1422-0067/24/4/3170

2.Meng-meng Wu, Xu Chen, Qing-xuan Xu, Lian-sheng Zang, Su Wang, Ming Li (co-corresponding author)*, Da Xiao*. Melanin Synthesis Pathway Interruption: CRISPR/Cas9-mediated Knockout of dopa decarboxylase (DDC) in Harmonia axyridis (Coleoptera: Coccinellidae).  2022. Journal of Insect Science.

//academic.oup.com/jinsectscience/article/22/5/1/6694719

3.Ming Li#, Ting Yang#, Michelle Bui, Stephanie Gamez, Tyler Wise, Nikolay P Kandul, Junru Liu, Lenissa Alcantara, Haena Lee, Jyotheeswara R Edula, Robyn Raban, Yinpeng Zhan, Yijin Wang, Nick DeBeaubien, Jieyan Chen, Hector M Sanchez C, Jared B Bennett, Igor Antoshechkin, Craig Montell, John M Marshall, Omar S Akbari. Suppressing mosquito populations with precision guided sterile males. 2021. Nature Communications.

//www.nature.com/articles/s41467-021-25421-w

4.Ming Li, Ting Yang, Nikolay P Kandul, Michelle Bui, Stephanie Gamez, Robyn Raban, Jared Bennett, Gregory C Lanzaro, Hanno Schmidt, Yoosook Lee, John M Marshall, Omar S Akbari. Development of a Confinable Gene-Drive System in the Human Disease Vector, Aedes aegypti. 2020. eLife.

//elifesciences.org/articles/51701

5.Ming Li (First author and co-corresponding author), Omar S Akbari, Bradley J White. Highly efficient site-specific mutagenesis in malaria mosquitoes using CRISPR. 2018. G3: Genes, Genomes, Genetics.

//pubmed.ncbi.nlm.nih.gov/29233915/

6.Ming Li, Michelle Bui, Ting Yang, Christian S Bowman, Bradley J White, Omar S Akbari. Germline cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, Aedes aegypti. 2017. Proceedings of the National Academy of Sciences.

//www.pnas.org/content/114/49/E10540

7.Ming Li, Lauren Yun Cook Au, Deema Douglah, Abigail Chong, Bradley J White, Patrick M Ferree, Omar S Akbari. Generation of heritable germline mutations in the jewel wasp Nasonia vitripennis using CRISPR/Cas9. 2017. Scientific Reports.

//www.nature.com/articles/s41598-017-00990-3