导师资格:硕士生导师
所在教研室/单位: 法医物证学教研室
E-mail:[email protected]
办公电话:+86-020-87330563
研究方向:1、 致力于通过组学和质谱学技术对新精神活性物质进行成瘾及中毒机制研究;2、 致力于通过药物晶体学方法结合天然药物化学研究毒品减毒降瘾机制。
个人简介
李良博士,博彩公司排名-博彩公司评级 副教授,主任法医师,硕士研究生导师,中山大学法医鉴定中心法医毒物室主任。2013年博士毕业于澳门科技大学中药质量研究国家重点实验室。主要从事新精神活性物质成瘾机制研究,获国家自然科学基金、广东省自然科学基金等资助,曾获澳门特别行政区科学技术奖(博士)。
主要研究领域
- 致力于通过组学和质谱学技术对新精神活性物质进行成瘾及中毒机制研究;
- 致力于通过药物晶体学方法结合天然药物化学研究毒品减毒降瘾机制。
代表性学术成果
- L. Li*, H.J. Cao, Z.Z. Zhou, Q.H. Wang*. Metabolomics analysis reveals how water extract of Gastrodia elata helps against heroin addiction. Parmacol. Res.-Chinese Med., 1000071, 2022. (母刊IF= 7.658, JCR-Q1)
- L. Li*, J.Y. Li, Z.Z. Zhou, K.H Xue*. Determination of Metabolic Phenotype and Potential Biomarkers in the Liver of Heroin Addicted Mice with Hepatotoxicity. Life Sci., 00243205, 2021 (IF= 5.037, JCR-Q1)
- J.Q. Li, Z.Z. Zhou, X.H. Tan*, L. Li*. Major and trace elements changes of female methamphetamine addicts during six months’ compulsory treatment: Biomarkers discover y. Forensic Sci. Int. 2021 (IF=2.395, Forensic medicine- JCR-Q1)
- H.J. Liu, Z.Z. Zhou*, L. Li*. Bergenin-isonicotinamide (1:1) cocrystal with enhanced solubility and investigation of its solubility behavior. J. Drug Del. Sci. Tec. 11571489. 2021 (IF=3.981, JCR-Q2)
- J.L. Zhou, L. Li#, Z.Z. Zhou*. Crystal structure, dissolution and pharmacokinetic study on a novel phosphodiesterase-4 inhibitor chlrobipram cocrystals. Int. J. Pharm. 576:11894. 2020 (IF=5.875, JCR-Q1)
- Y.Y. Zhang, L. Li#, Z.Z. Zhou*. Simultaneous determination of metabolic and elemental markers in methamphetamine-induced hepatic injury to rats. Anal. Bio. Chem. 411: 3361, 2019 (IF=4.157, JCR-Q2)
- Y.M. Luo, L. Li*, Z.Z. Zhou*. Luteolin cocrystals: Characterization, evaluation of solubility, oral bioavailability and theoretical calculation. J. Drug Del. Sci. Tec.50: 248, 2019 (IF=3.468, JCR-Q2)
- L. Li, T. Yi, Chris. W.K. Lam. Inhibition of Hunan Efflux Transporter ABCC2(MRP2) by Self-emulsifying Drug delivery System: Influences of Concentration and Combination of Excipients. J Pharm Pharm Sci. 17, 447-460. 2014.(IF=2.920, JCR-Q3)
- L. Li, T. Yi, Chris. W.K. Lam*. Interactions between Human Multidrug Resistance Related Protein (MRP2; ABCC2) and Excipients used in Self-emulsifying Drug Delivery Systems (SEDDS). Int. J. Pharm. 447(1-2), 192-198, 2013 (IF= 3.785, JCR-Q1)
- L. Li, T. Yi, Chris. W.K. Lam*. Effects of spray-drying and choice of solid carriers on concentrations of labrasol and transcutol in solid self-microemulsifying drug delivery systems(SMEDDS). Molecules. 18, 545-560, 2013(IF= 2.428, JCR-Q2)
- T. Yi, L. Li, Chris. W.K. Lam. A pharmaceutical composition for treating cardiovascular and cerebrovascular diseases and method of manufacturing the same. 2013, Australia Innovation Patent. 2013101145.