导师资格：博士生导师

所在教研室/单位： 寄生虫学教研室

行政职务： 寄生虫学教研室主任

E-mail：[email protected]

通信地址： 广州市中山二路74号，博彩公司排名-博彩公司评级 医学科技综合楼

办公电话：020-87335900

研究方向：重要病原感染与免疫调控、药物研究

个人简介

 吕志跃博士，博彩公司排名-博彩公司评级 教授，博士生导师，教育部课程思政教学名师，中山大学逸仙优秀学者，泰国玛希隆大学客座教授。现任博彩公司排名 党委委员，中山大学热带病防治研究教育部重点实验室副主任，中山大学医学实验教学中心常务副主任。2005年于中南大学湘雅医学院获博士学位，2007年于博彩公司排名-博彩公司评级 博士后出站并留校。2012年，被选拔为国家留学基金“青年骨干教师”赴美国韦恩州立大学医学院公派留学1年。2019-2021年，中组部选派挂职兼任海南医学院副校长。近年来一直从事病原生物-宿主适应性、重要入侵病原快速溯源等领域的研究工作。主持比尔及梅琳达·盖茨基金会资助重大项目、国家重点研发项目课题、国家自然科学基金面上项目等26项课题，经费总额超过一千五百万元。在国内外专业学术期刊发表论文超过100篇，其中SCI论文60余篇（通讯作者/共同通讯作者34篇，其中中科院一区14篇，二区8篇）。获得10项国家授权专利和3项软件著作权。主编、副主编国家规划教材7部。指导学生获得5项“全国大学生基础医学创新研究暨实验设计大赛”总决赛一等奖/金奖和1项全国“医学+X”大学生虚拟仿真优秀作品展示会金奖

学术成果

重要学术研究成果与贡献：
学术论著（近5年）：      

  1. Bingcheng Yu, Rongjian Zhan, Yue Hu*, Zhiyue Lv*. Mass spectrometry imaging: AnBingcheng  emerging technology in medical parasitology. Anal Chem. 2024.3.
  2. Hui Huang, Zhongyuan Zhang, Mengdan Xing, Zihan Jin, Yue Hu, Minyu Zhou, Hang Wei, Yiwen Liang, Zhiyue Lv*. Angiostrongylus cantonensis induces energy imbalance and dyskinesia in mice by reducing the expression of melanin-concentrating hormone. Parasites & Vectors. 2024. 4
  3. Minyu Zhou, Lian Xu, Dahua Xu, Wen Chen, Jehangir Khan, Yue Hu, Hui Huang,  Hang Wei, Yiqing Zhang, Phiraphol Chusongsang, Kanthi Tanasarnprasert, Xiang Hu; Yanin Limpanont*, Zhiyue Lv*. Chromosome-scale genome of the human blood fluke Schistosoma mekongi and its implications for public health. Infect Dis Poverty. 2023,10.
  4. Jitrawadee Intirach , Xin Lv, Qian Han , Zhiyue Lv*, Tao Chen*. Morphological and Molecular Identification of Hard Ticks in Hainan Island, China. Genes (Basel) . 2023, 14(8):1592.
  5. Zhou HL, Lu YT, Wei H, Chen YX, Limpanon y, Dekumyoy P, Huang P,  Shi PY, Lv ZY*. Stat3/IL-6 signaling mediates sustained pneumonia induced by Angiostrongylus cantonensis. PLOS Neglect Trop D, 2022,16(5):e0010461.
  6. Lin QY, Lin GT, Zhang F, Xiang XY, Zhang YH, Wang JC, Jin YM, Hai YP, Tao-Wu, Lv ZY*, Xiang W*. Clinical and epidemiological investigation of a child with asymptomatic COVID-19 infection following reoccurrence. Health Inf Sci Syst. 2022,10(1):18. doi: 10.1007/s13755-022-00188-6.
  7. Chen JS, Hu Y, Shao CX, Zhou HY, Lv ZY*. The Imprinted PARAFILM as a new carrier material for dried plasma spots (DPSs) utilizing Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) in phospholipidomics. Front Chem. 2021, 9:801043.
  8. Zhou HL, Zhou MY, Hu Y, Limpanont Y, Ma YB, Huang P, Dekumyoy P, Maleewong W, Lv ZY*. TNF-α triggers RIP1/FADD/caspase-8 mediated apoptosis of astrocytes and RIP3/MLKL mediated necroptosis of neurons induced by Angiostrongylus cantonensis infection. Cell Mol Neurobiol. 2021.doi: 10.1007/s10571-021-01063-w.  
  9. Hongli Zhou, Xiaojing Zeng, Dongchen Sun, Zhe Chen, Weixin Chen, Liwei Fan, Yanin Limpanont, Paron Dekumyoy, Wanchai Maleewong, Zhiyue Lv*. Monosexual cercariae of Schistosoma japonicum infection protects against DSS-induced colitis by shifting the Th1/Th2 balance and modulating the gut microbiota. Front Microbiol. 2021,11:606605. doi: 10.3389/fmicb.2020.606605.
  10. Song LG*, Xie QX, Lao HL, Lv ZY*. Human coronaviruses and therapeutic drug discovery. Infect Dis Poverty. 2021,10(1):28. doi: 10.1186/s40249-021-00812-9.
  11. Zhou MY, Cao K, Huang H, Luo XJ, Wang Y, Ma WK, Lv ZY*. Neonatal oral myiasis caused by the larvae of Sarcophaga ruficornis (Diptera: Sarcophagidae): a case report. BMC Infec Dis. 2021, doi : 10.1186/s12879-021-06742-z.
  12. Yue Hu, Jiansong Chen, Yiyue Xu, Hongli Zhou, Ping Huang, Ma Yubin, Minzhao Gao, Shaoyun Cheng, Haiyun Zhou, Zhiyue Lv*. Alterations of gut microbiome and metabolite profiling in mice infected by Schistosoma japonicum. Front Immunol. 2020,10.3389/fimmu.2020.569727.
  13. Yue Hu, Hanguo Xie, Minzhao Gao, Ping Huang, Hongli Zhou, Ma Yubin, Minyu Zhou, Jinying Liang, Jun Yang*, Zhiyue Lv*. Dynamic of composition and diversity of gut microbiota in Triatoma rubrofasciata in different developmental stages and environmental conditions. Front Cell Infect Microbiol. 2020, 10. 3389/ fcimb. 2020. 587708.
  14. Huang P, Zhou MY, Cheng SY, Hu Y, Gao MZ, Ma YB, Limpanont Y, Zhou HL, Paron D, Cheng YX, Lv ZY*. Myricetin possesses anthelmintic activity and attenuates hepatic fibrosis via modulating TGFβ1 and Akt signaling and shifting Th1/Th2 balance in Schistosoma japonicum-infected mice. Front Immunol. 2020,10.3389/fimmu.2020.00593.
  15. Zhou HL, Chen Z, Limpanont Y, Hu Y, Ma YB, Huang P, Paron D, Zhou MY, Cheng YX, Lv ZY*. Necroptosis and caspase-2-mediated apoptosis of astrocytes and neurons, but not microglia, of rat hippocampus and parenchyma caused by Angiostrongylus cantonensis infection. Front Microbiol. 2020,10:3126.
  16. Xu L, Xu M, Sun X, Xu JY, Zeng X, Shan D, Yuan DJ, He P, He WM, Yang YL, Luo SQ, Wei J, Wu XY, Liu Z, Xu XM, Dong ZS, Song LG, Zhang BB, Yu ZL, Wang LF, Zhang C, Fang XD, Gao Q*, Lv ZY*, Wu ZD*. The genetic basis of adaptive evolution in parasitic environment from the Angiostrongylus cantonensis genome. PLOS Neglect Trop D, 2019,13(11):e0007846.
  17. Shen SS, Qu XY, Zhang WZ, Li J, Lv ZY *. Infection against infection: Parasite antagonism against parasites, viruses and bacteria. Infect Dis Poverty. 2019,8(1):49.
  18. Hu Y, Gao MZ, Huang P, Zhou HL, Ma YB, Zhou MY, Cheng SY, Xie HG*, Lv ZY*.Taxonomic integrative and phylogenetic identification of the first recorded Triatoma rubrofasciata in Zhangzhou, Fujian Province and Maoming, Guangdong Province, China. Infect Dis Poverty. 2019, 8(1):70.
  19. Deng MH, Zhong LY, Kamolnetr O, Limpanont Y, Lv ZY*. Detection of helminths by loop-mediated isothermal amplification assay: A review of updated technology and future outlook. Infect Dis Poverty. 2019,8(1):20.
  20. Zhu GL, Tang YY, Limpanont Y, Wu ZD, Li J*, Lv ZY*. Zoonotic parasites carried by invasive alien species in China. Infect Dis Poverty. 2019 8(1):2.
  21. Liu XL, Zhu GL, Cai CN, Lv ZY*, Li J*. Clonorchiasis sinensis detected by laparoscopic exploration of biliary tracts in two patients with obstructive jaundice. BMC Infec Dis. 2019,19(1):33.
  22. Lu XT, Gu QY, Limpanont Y, Song LG, Wu ZD, Okanurak K, Lv ZY*. Snail-borne parasitic diseases: an update on global epidemiological distribution, transmission interruption and control methods. Infect Dis Poverty. 2018,7(1):28.

获奖荣誉

2010年入选为广东省高等学校“千百十”工程培养对象。2012年至今3次评为中山大学“优秀学生导师”。5次评为中山大学“优秀党员”或中山大学“优秀党务工作者”。2022年获广东省柯麟医学教育基金会优秀临床医学中青年教师突出贡献奖。

学术兼职

 国家卫生健康标准委员会专业委员会委员，广东省寄生虫学会秘书长，中国地方病协会热带病专业委员会委员，中华预防医学会医学寄生虫学分会教育学组委员会委员，广州市医学会细胞形态学诊断分会常务委员，《热带医学杂志》、《热带病与寄生虫学》常务编委。