个人简介
工作经历
2024-01至今：副教授，博彩公司排名 ，中山大学
2022-08至2024-01：特聘副研究员，博彩公司排名 ，中山大学
2020-08至2022-08：博士后，博彩公司排名 ，中山大学
教育经历
2015-09至2020-06：博士，外科学，附属第一医院，中山大学
2010-09至2015-06：本科，临床医学，博彩公司排名 ，中山大学
学术成果
学术论文
1. Luo P#, Chen X#, Gao F, Xiang AP, Deng C, Xia K*, Gao Y*. Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Rescue Testicular Aging. Biomedicines. 2024.
2. Xia K#, Wang F#, Tan Z#, Zhang S#, Lai X, Ou W, Yang C, Chen H, Peng H, Luo P, Hu A, Tu X, Wang T, Ke Q, Deng C*, Xiang AP*. Precise correction of Lhcgr mutation in stem Leydig cells by prime editing rescues hereditary primary hypogonadism in mice. Advanced Science. 2023.
3. Xia K, Yu J, Liu G, Chen H, Ge R, Deng C. Editorial: Aging and male hypogonadism. Frontiers in Endocrinology. 2023.
4. Su Z#, Liu Z#, Lei W#, Xia K#, Xiao A, Hu Z, Zhou M, Zhu F, Tian J, Yang M, Wang D, Xiang AP, Nie J. Hyperhomocysteinemia lowers serum testosterone concentration via impairing testosterone production in Leydig cells. Cell Biology and Toxicology. 2023.
5. Xie Q#, Cao H#, Xia K#, Gao Y*, Deng C*. Prenatal DEHP Exposure Induces Premature Testicular Aging by Promoting Leydig Cell Senescence through the MAPK Signaling Pathways. Advanced Biology. 2023.
6. Xia K#, Wang F#, Lai X#, Dong L#, Luo P, Zhang S, Yang C, Chen H, Ma Y, Huang W, Ou W, Li Y, Feng X, Yang B, Liu C, Lei Z, Tu X, Ke Q, Mao FF, Deng C*, Xiang AP*. AAV-mediated gene therapy produces fertile offspring in the Lhcgr-deficient mouse model of Leydig cell failure. Cell Reports Medicine. 2022.
7. Xie Q#, Luo P#, Xia K#, Li Z#, Xu Z*, Su C*, Deng C*. 46,XY disorders of sex development: the use of NGS for prevalent variants. Human Genetics. 2022.
8. Chen H#, Xia K#, Huang W#, Li H, Wang C, Ma Y, Chen J, Luo P, Zheng S, Wang J, Wang Y, Dong L, Tan Z, Lai X, Mao FF, Li W, Liang X, Wang T, Xiang AP, Qiong K*. Autologous transplantation of thecal stem cells restores ovarian function in nonhuman primates. Cell Discovery. 2021.
9. Feng X#, Xia K#, Ke Q#, Deng R, Zhuang J, Wan Z, Luo P, Wang F, Zang Z, Sun X, Xiang AP, Tu X*, Gao Y*, Deng C*. Transplantation of encapsulated human Leydig-like cells: A novel option for the treatment of testosterone deficiency. Molecular and Cellular Endocrinology. 2021.
10. Luo P#, Feng X#, Deng R#, Wang F, Zhang Y, Li X, Zhang M, Wan Z, Xiang AP, Xia K*, Gao Y*, Deng C*. An autofluorescence-based isolation of Leydig cells for testosterone deficiency treatment. Molecular and Cellular Endocrinology. 2021.
11. Xia K, Ma Y, Feng X, Deng R, Ke Q, Xiang AP*, Deng C*. Endosialin defines human stem Leydig cells with regenerative potential. Human Reproduction. 2020.
12. Xia K#, Chen H#, Wang J#, Feng X#, Gao Y, Wang Y, Deng R, Wu C, Luo P, Zhang M, Wang C, Zhang Y, Zhang Y, Liu G, Tu X, Sun X, Li W, Ke Q*, Deng C*, Xiang AP*. Restorative functions of autologous stem Leydig cell transplantation in a testosterone-deficient non-human primate model. Theranostics. 2020.
科研项目
主持项目
1. 国家自然科学基金面上项目，2024-01至2027-12，49万
2. 国家自然科学基金青年项目，2022-01至2024-12，30万
3. 中国博士后基金面上项目，2021-10至2022-07，8万
4. 广东省自然科学基金面上项目，2022-01至2024-12，10万
5. 广州市基础与应用基础研究“启航”类项目，2024-01至2025-12，5万
6. 中山大学高校基本科研业务费，2022-01至2022-12，8.53万
