导师资格：硕士生导师

所在教研室/单位： 人体解剖学教研室

E-mail：[email protected]

研究方向：）基于微流控技术的类器官制备与应用；2）纳米材料的毒理学评估及应用开发；3）基于类器官技术的组织再生；4）基于类器官技术的临床精准医学应用。

个人简介

蒋盛威，人体解剖学系副教授、硕士生导师。2014年毕业于中南大学湘雅医学院预防医学专业，获得医学学士学位。2017年毕业于厦门大学公共卫生学院转化医学专业，获得医学硕士学位。2021年毕业于清华大学清华-伯克利深圳学院精准医学与公共健康专业，获得医学博士学位。 2021年至2023年在深圳大学总医院进行博士后研究工作。2023年10月引进到岗，同时入选“逸仙学者”计划。主要研究方向为1）基于微流控技术的类器官制备与应用；2）纳米材料的毒理学评估及应用开发；3）基于类器官技术的组织再生；4）基于类器官技术的临床精准医学应用。以主要作者在Cell Reports Medicine（2020）、Nature Machine Intelligence（2020）、Advanced Materials（2023）、Advanced Healthcare Materials（2023, Cover paper）等高水平学术期刊发表论文10余篇。主持科研项目2项，包括国自然青年项目，博士后基金面上项目。

学术成果

代表性论著

  1. Jiang S, Zhao H, Zhang W, et al. An Automated Organoid Platform with Inter-organoid Homogeneity and Inter-patient Heterogeneity. Cell Reports Medicine. 2020, 1(9): 100161. (IF:14.3，中科院一区)
  2. Ye L, Jiang S (co-first author), Hu J, et al. Induction of Metabolic Reprogramming in Kidney by Singlet Diradical Nanoparticles[J]. Advanced Materials, 2023: 2301338. (IF:29.4，中科院一区)
  3. Jiang S, Deng T, Cheng H, et al. Macrophage-organoid co-culture model for identifying treatment strategies against macrophage-related gemcitabine resistance[J]. Journal of Experimental & Clinical Cancer Research, 2023, 42(1): 199. (IF:11.3，中科院一区)
  4. Jiang S, Liu W, Shi D, et al. Black Phosphorus as a Targeting PPAR‐γ Agonist to Reverse Chemoresistance in Patient‐derived Organoids, Mice, and Pancreatic Tumor Cells[J]. Advanced Healthcare Materials, 2023: 2301324. (IF:10，中科院一区)
  5. Yong W, Mengqi J, Jiang S (co-first author), et al. Augmenting Vascular Disease Diagnosis by Vasculature-aware Unsupervised Learning. Nature Machine Intelligence. 2020, 2(6): 337-346. (co-first author) (IF:23.8，中科院一区)
  6. He C, Ruan F, Jiang S (co-first author), et al. Black Phosphorus Quantum Dots Cause Nephrotoxicity in Organoids, Mice, and Human Cells. Small, 2020, 16(22): 2001371. (IF:13.3，中科院一区)
  7. Zeng L. Raltitrexed as a synergistic hyperthermia chemotherapy drug screened in patient-derived colorectal cancer organoids. Cancer Biology & Medicine, 2021, 18(2): 1-31. (Corresponding author) (IF:5.5，中科院二区)
  8. Zhang W, Li D, Jiang S (co-first author), et al. Microfluidic droplets as structural templates for Matrigel to enable 1-week large organoid modeling. Chemical Engineering Science, 2021: 116632. (co-first author) (IF:4.7，中科院二区)
  9. Jiang S, Lin Y, Yao H, et al. The role of unfolded protein response and ER-phagy in quantum dots-induced nephrotoxicity: an in vitro and in vivo study. Archives of Toxicology. 2018(1): 1-14. (IF:6.1，中科院小类一区)
  10. He C#, Jiang S# (co-first author), Jin H#, et al. Mitochondrial electron transport chain identified as a novel molecular target of SPIO nanoparticles mediated cancer-specific cytotoxicity. Biomaterials, 2016, 83: 102-114. (co-first author) (IF:14，中科院一区)
  11. He C#, Jiang S# (co-first author), Lin Y, Yao H, et al. Endoplasmic reticulum stress mediates inflammatory response triggered by ultra-small superparamagnetic iron oxide nanoparticles in hepatocytes. Nanotoxicology. 2018, 12(10): 1198-1214. (IF:5.0，中科院二区)
  12. He C#, Jiang S# (co-first author), et al. High-content analysis for mitophagy response to nanoparticles: A potential sensitive biomarker for nanosafety assessment. Nanomedicine. 2019, 15(1): 59-69. (IF:5.4，中科院二区)

获奖荣誉

以主要作者在Cell Reports Medicine（2020）、Nature Machine Intelligence（2020）、Advanced Materials（2023）、Advanced Healthcare Materials（2023, Cover paper）等高水平学术期刊发表论文10余篇。主持科研项目2项，包括国自然青年项目，博士后基金面上项目。